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Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells

BACKGROUND: Human cervical cancer oncoprotein 1 (HCCR-1), reported as a negative regulator of p53, is over-expressed in a variety of human cancers. However, it is yet unknown whether HCCR-1 plays any role in pancreatic cancer development. The aim of this study was to investigate the effect of epider...

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Detalhes bibliográficos
Main Authors: Xu, Zekuan, Zhang, Yi, Jiang, Jiakai, Yang, Yang, Shi, Ruihua, Hao, Bo, Zhang, Zhihong, Huang, Zuhu, Kim, Jin W, Zhang, Guoxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880295/
https://ncbi.nlm.nih.gov/pubmed/20423485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-161
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