The Functions of the HIV1 protein Vpr and its action through the DCAF1•DDB1•Cullin4 ubiquitin ligase

Among the proteins encoded by human and simian immunodeficiency viruses (HIV and SIV) at least three, Vif, Vpu and Vpr, subvert cellular ubiquitin ligases to block the action of anti-viral defenses. This review focuses on Vpr and its HIV2/SIV counterparts, Vpx and Vpr, which all engage the DDB1•Cull...

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Bibliographic Details
Main Authors: Casey, Laurieann, Wen, Xiaoyun, de Noronha, Carlos M.C.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880205/
https://ncbi.nlm.nih.gov/pubmed/20347598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2010.02.018
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