Nitro-Oleic Acid Inhibits Firing and Activates TRPV1- and TRPA1-Mediated Inward Currents in Dorsal Root Ganglion Neurons from Adult Male Rats

Nitro-oleic acid (OA-NO(2)), an electrophilic fatty acid by-product of nitric oxide and nitrite reactions, is present in normal and inflamed mammalian tissues at up to micromolar concentrations and exhibits anti-inflammatory signaling actions. The effects of OA-NO(2) on cultured dorsal root ganglion...

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Autors principals: Sculptoreanu, A., Kullmann, F. A., Artim, D. E., Bazley, F. A., Schopfer, F., Woodcock, S., Freeman, B. A., de Groat, W. C.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2010
Matèries:
Cellular and Molecular
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879937/
https://ncbi.nlm.nih.gov/pubmed/20304940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.163154
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