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Effects of ralfinamide, a Na(+) channel blocker, on firing properties of nociceptive dorsal root ganglion neurons of adult rats

Recent studies revealed that ralfinamide, a Na(+) channel blocker, suppressed tetrodotoxin-resistant Na(+) currents in dorsal root ganglion (DRG) neurons and reduced pain reactions in animal models of inflammatory and neuropathic pain. Here, we investigated the effects of ralfinamide on Na(+) curren...

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Detalhes bibliográficos
Main Authors: Yamane, Hana, de Groat, William C., Sculptoreanu, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117901/
https://ncbi.nlm.nih.gov/pubmed/17707373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2007.07.010
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