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The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci
The critical initial step in V(D)J recombination, binding of RAG1 and RAG2 to recombination signal sequences flanking antigen receptor V, D, and J gene segments, has not previously been characterized in vivo. Here we demonstrate that RAG protein binding occurs in a highly focal manner to a small reg...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879619/ https://ncbi.nlm.nih.gov/pubmed/20398922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.03.010 |
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