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Trichostatin A enhances acetylation as well as protein stability of ERα through induction of p300 protein

INTRODUCTION: Trichostatin A (TSA) is a well-characterized histone deacetylase (HDAC) inhibitor. TSA modifies the balance between HDAC and histone acetyltransferase activities that is important in chromatin remodeling and gene expression. Although several previous studies have demonstrated the role...

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Detalhes bibliográficos
Main Authors: Kim, Sung-Hye, Kang, Hyun-Jin, Na, Hyelin, Lee, Mi-Ock
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879569/
https://ncbi.nlm.nih.gov/pubmed/20388208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2562
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