Structural determinants of specific DNA-recognition by the THAP zinc finger

Human THAP1 is the prototype of a large family of cellular factors sharing an original THAP zinc-finger motif responsible for DNA binding. Human THAP1 regulates endothelial cell proliferation and G1/S cell-cycle progression, through modulation of pRb/E2F cell-cycle target genes including rrm1. Recen...

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Bibliographic Details
Main Authors: Campagne, Sébastien, Saurel, Olivier, Gervais, Virginie, Milon, Alain
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879526/
https://ncbi.nlm.nih.gov/pubmed/20144952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq053
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