Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1

The REF/ALY mRNA export adaptor binds TAP/NXF1 via an arginine-rich region, which overlaps with its RNA-binding domain. When TAP binds a REF:RNA complex, it triggers transfer of the RNA from REF to TAP. Here, we have examined the effects of arginine methylation on the activities of the REF protein i...

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Bibliografske podrobnosti
Main Authors: Hung, Ming-Lung, Hautbergue, Guillaume M., Snijders, Ambrosius P. L., Dickman, Mark J., Wilson, Stuart A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879514/
https://ncbi.nlm.nih.gov/pubmed/20129943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq033
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