Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1

The REF/ALY mRNA export adaptor binds TAP/NXF1 via an arginine-rich region, which overlaps with its RNA-binding domain. When TAP binds a REF:RNA complex, it triggers transfer of the RNA from REF to TAP. Here, we have examined the effects of arginine methylation on the activities of the REF protein i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hung, Ming-Lung, Hautbergue, Guillaume M., Snijders, Ambrosius P. L., Dickman, Mark J., Wilson, Stuart A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2010
Pynciau:
RNA
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879514/
https://ncbi.nlm.nih.gov/pubmed/20129943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq033
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