Insights in the glycosylation steps during biosynthesis of the antitumor anthracycline cosmomycin: characterization of two glycosyltransferase genes

Glycosylation pattern in cosmomycins is a distinctive feature among anthracyclines. These antitumor compounds possess two trisaccharide chains attached at C-7 and C-10, each of them with structural variability, mainly at the distal deoxysugar moieties. We have characterized a 14-kb chromosomal regio...

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Main Authors: Garrido, Leandro M., Lombó, Felipe, Baig, Irfan, Nur-e-Alam, Mohammad, Furlan, Renata L. A., Borda, Charlotte C., Braña, Alfredo, Méndez, Carmen, Salas, José A., Rohr, Jürgen, Padilla, Gabriel
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879347/
https://ncbi.nlm.nih.gov/pubmed/16810496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-006-0453-z
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