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Characterization of the pattern of the nongenomic signaling pathway through which TCDD-induces early inflammatory responses in U937 human macrophages

2,3,7,8-Tetrachlorodibenzo(p)dioxin (TCDD) has been known to induce inflammatory signaling in a number of cell types and tissues. We found that in U937 macrophages TCDD causes rapid activation of cytosolic phospholipase A2 (cPLA2) within 30 min as judged by the increase in the serine 505 phosphoryla...

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Detalhes bibliográficos
Main Authors: Sciullo, Eric M., Dong, Bin, Vogel, Chris F.A., Matsumura, Fumio
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879335/
https://ncbi.nlm.nih.gov/pubmed/19162293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemosphere.2008.11.010
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