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TCDD-induced Cyclooxygenase-2 Expression Is Mediated by the Nongenomic Pathway in Mouse MMDD1 Macula Densa Cells and Kidneys
Cyclooxygenase-2 (Cox-2) plays a critical role in TCDD-induced hydronephrosis in mouse neonates. In this study we found that induction of Cox-2 by TCDD in MMDD1, a mouse macula densa cell line, is accompanied with a rapid increase in the enzymatic activity of cytosolic phospholipase A2 (cPLA2) as we...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796630/ https://ncbi.nlm.nih.gov/pubmed/19782052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.08.031 |
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