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Cystine 186–cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption
Tissue factor (TF) on cell surfaces resides mostly in a cryptic state. It is not entirely clear how cryptic TF differs from procoagulantly active TF and how deencryption occurs. Here, we critically evaluated the importance of cystine 186–cystine 209 (Cys186-Cys209) bond formation for TF procoagulant...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879102/ https://ncbi.nlm.nih.gov/pubmed/20237315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-241356 |
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