CD95/Fas promotes tumour growth

CD95 (also called Fas and APO-1) is a prototypical death receptor that regulates tissue homeostasis mainly in the immune system through induction of apoptosis 1-3. During cancer progression CD95 is frequently downregulated or cells are rendered apoptosis resistant 4,5 raising the possibility that lo...

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Bibliographic Details
Main Authors: Chen, Lina, Park, Sun-Mi, Tumanov, Alexei V., Hau, Annika, Sawada, Kenjiro, Feig, Christine, Turner, Jerrold R., Fu, Yang-Xin, Romero, Iris, Lengyel, Ernst, Peter, Marcus E.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879093/
https://ncbi.nlm.nih.gov/pubmed/20505730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09075
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