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Influenza A viruses with truncated NS1 as modified live virus vaccines: Pilot studies of safety and efficacy in horses

REASONS FOR PERFORMING STUDY: A reverse genetics rescue system for equine influenza virus and the construction of three NS1 mutant viruses encoding carboxy-terminally truncated NS1 proteins of 73, 99 or 126 amino acids, have been previously described (Quinlivan et al., J. Virology 79, 8431–8439, 200...

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Detalhes bibliográficos
Main Authors: Chambers, Thomas M., Quinlivan, Michelle, Sturgill, Tracy, Cullinane, Ann, Horohov, David W., Zamarin, Dmitriy, Arkins, Sean, García-Sastre, Adolfo, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878972/
https://ncbi.nlm.nih.gov/pubmed/19301588
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