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Expanding the Range of ‘Druggable’ Targets with Natural Product-based Libraries: An Academic Perspective
Existing drugs address a relatively narrow range of biological targets. As a result, libraries of drug-like molecules have proven ineffective against a variety of challenging targets, such as protein–protein interactions, nucleic acid complexes, and antibacterial modalities. In contrast, natural pro...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878877/ https://ncbi.nlm.nih.gov/pubmed/20202892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2010.02.001 |
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