Activated T-Cells Inhibit Neurogenesis by Releasing Granzyme B: Rescue by Kv1.3 Blockers

There is a great need for pharmacological approaches to enhance neural progenitor cell (NPC) function particularly in neuroinflammatory diseases with failed neuroregeneration. In diseases such as multiple sclerosis and stroke, T-cell infiltration occurs in periventricular zones where NPCs are locate...

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Autors principals: Wang, Tongguang, Lee, Myoung-Hwa, Johnson, Tory, Allie, Rameeza, Hu, Lina, Calabresi, Peter A., Nath, Avindra
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878660/
https://ncbi.nlm.nih.gov/pubmed/20371822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0311-10.2010
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