Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly

Break-induced replication (BIR) is an efficient homologous recombination (HR) pathway employed to repair a DNA double-strand break (DSB) when homology is restricted to one end. All three major replicative DNA polymerases are required for BIR, including the otherwise nonessential Pol32 subunit. Here...

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Detalhes bibliográficos
Main Authors: Lydeard, John R., Lipkin-Moore, Zachary, Sheu, Yi-Jun, Stillman, Bruce, Burgers, Peter M., Haber, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878651/
https://ncbi.nlm.nih.gov/pubmed/20516198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1922610
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