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Solution Conformation and Dynamics of the HIV-1 Integrase Core Domain
The human immunodeficiency virus type 1 (HIV-1) integrase (IN) is a critical enzyme involved in infection. It catalyzes two reactions to integrate the viral cDNA into the host genome, 3′ processing and strand transfer, but the dynamic behavior of the active site during catalysis of these two process...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878568/ https://ncbi.nlm.nih.gov/pubmed/20363759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113407 |
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