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Solution Conformation and Dynamics of the HIV-1 Integrase Core Domain
The human immunodeficiency virus type 1 (HIV-1) integrase (IN) is a critical enzyme involved in infection. It catalyzes two reactions to integrate the viral cDNA into the host genome, 3′ processing and strand transfer, but the dynamic behavior of the active site during catalysis of these two process...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878568/ https://ncbi.nlm.nih.gov/pubmed/20363759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113407 |
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