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Solution Conformation and Dynamics of the HIV-1 Integrase Core Domain

The human immunodeficiency virus type 1 (HIV-1) integrase (IN) is a critical enzyme involved in infection. It catalyzes two reactions to integrate the viral cDNA into the host genome, 3′ processing and strand transfer, but the dynamic behavior of the active site during catalysis of these two process...

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Bibliografski detalji
Glavni autori: Fitzkee, Nicholas C., Masse, James E., Shen, Yang, Davies, David R., Bax, Ad
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878568/
https://ncbi.nlm.nih.gov/pubmed/20363759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113407
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