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Solution Conformation and Dynamics of the HIV-1 Integrase Core Domain

The human immunodeficiency virus type 1 (HIV-1) integrase (IN) is a critical enzyme involved in infection. It catalyzes two reactions to integrate the viral cDNA into the host genome, 3′ processing and strand transfer, but the dynamic behavior of the active site during catalysis of these two process...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fitzkee, Nicholas C., Masse, James E., Shen, Yang, Davies, David R., Bax, Ad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878568/
https://ncbi.nlm.nih.gov/pubmed/20363759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.113407
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