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α-Hemoglobin Stabilizing Protein (AHSP), a Kinetic Scheme of the Action of a Human Mutant, AHSP(V56G)

A kinetic analysis has been made of the interaction of α-Hb chains with a mutant α-hemoglobin stabilizing protein, AHSP(V56G), which is the first case of an AHSP mutation associated with clinical symptoms of mild thalassemia syndrome. The chaperone AHSP is thought to protect nascent α chains until f...

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Detalhes bibliográficos
Main Authors: Brillet, Thomas, Baudin-Creuza, Véronique, Vasseur, Corinne, Domingues-Hamdi, Elisa, Kiger, Laurent, Wajcman, Henri, Pissard, Serge, Marden, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878560/
https://ncbi.nlm.nih.gov/pubmed/20371604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098491
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