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GDP-Tubulin Incorporation into Growing Microtubules Modulates Polymer Stability
Microtubule growth proceeds through the endwise addition of nucleotide-bound tubulin dimers. The microtubule wall is composed of GDP-tubulin subunits, which are thought to come exclusively from the incorporation of GTP-tubulin complexes at microtubule ends followed by GTP hydrolysis within the polym...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878515/ https://ncbi.nlm.nih.gov/pubmed/20371874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.099515 |
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