The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2

Little is known of how Toll-like receptor (TLR) ligands are processed after recognition by TLRs. This study was therefore designed to investigate how the TLR2 ligand FSL-1 is processed in macrophages after recognition by TLR2. FSL-1 was internalized into the murine macrophage cell line, RAW264.7. Bo...

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Detalhes bibliográficos
Main Authors: Shamsul, Haque M, Hasebe, Akira, Iyori, Mitsuhiro, Ohtani, Makoto, Kiura, Kazuto, Zhang, Diya, Totsuka, Yasunori, Shibata, Ken- ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878470/
https://ncbi.nlm.nih.gov/pubmed/20113368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03232.x
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