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CD13 Restricts TLR4 Endocytic Signal Transduction in Inflammation

Dysregulation of the innate immune response underlies numerous pathological conditions. The Toll-like Receptor 4 (TLR4) is the prototypical sensor of infection or injury that orchestrates the innate response via sequential activation of both cell-surface and endocytic signaling pathways that trigger...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Ghosh, Mallika, Subramani, Jaganathan, Rahman, M. Mamunur, Shapiro, Linda H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402264/
https://ncbi.nlm.nih.gov/pubmed/25801433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403133
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