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Methoxypyridines in the Synthesis of Lycopodium Alkaloids: Total Synthesis of (±)–Lycoposerramine R

[Image: see text] A methoxypyridine serves as a masked pyridone in a concise synthesis of the Lycopodium alkaloid lycoposerramine R, which has been prepared for the first time. The key step of the synthesis is the use of an Eschenmoser Claisen rearrangement to forge a key quaternary carbon center.

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Bibliografiske detaljer
Main Authors: Bisai, Vishnumaya, Sarpong, Richmond
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878394/
https://ncbi.nlm.nih.gov/pubmed/20441180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100823t
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