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Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of Nuclear Factor-κB
The scaffolding PDZ-domain containing protein MDA-9/syntenin is a tandem PDZ protein overexpressed in human melanoma, and breast and gastric cancer cells. MDA-9/syntenin affects cancer cell motility and invasion through distinct biochemical and signaling pathways, including focal adhesion kinase (FA...
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| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878370/ https://ncbi.nlm.nih.gov/pubmed/20228839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.65 |
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