Adjuvanted Influenza Vaccine Administered Intradermally Elicits Robust Long-Term Immune Responses that Confer Protection from Lethal Challenge

BACKGROUND: The respiratory illnesses caused by influenza virus can be dramatically reduced by vaccination. The current trivalent inactivated influenza vaccine is effective in eliciting systemic virus-specific antibodies sufficient to control viral replication. However, influenza protection generate...

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Detalhes bibliográficos
Main Authors: Martin, Maria del P., Seth, Shaguna, Koutsonanos, Dimitrios G., Jacob, Joshy, Compans, Richard W., Skountzou, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878352/
https://ncbi.nlm.nih.gov/pubmed/20531947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010897
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