GAB2 Amplifications Refine Molecular Classification of Melanoma

PURPOSE: Gain-of-function mutations in BRAF, NRAS, or KIT are associated with distinct melanoma subtypes with KIT mutations and/or copy number changes frequently observed among melanomas arising from sun-protected sites, such as acral skin (palms, soles, and nail bed) and mucous membranes. GAB2 has...

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Detalhes bibliográficos
Main Authors: Chernoff, Karen A., Bordone, Lindsey, Horst, Basil, Simon, Katherine, Twadell, William, Lee, Keagan, Cohen, Jason A., Wang, Shuang, Silvers, David N., Brunner, Georg, Celebi, Julide Tok
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878201/
https://ncbi.nlm.nih.gov/pubmed/19509136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0280
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