Cocaine Vaccine for the Treatment of Cocaine Dependence in Methadone Maintained Patients: A Randomized Double-Blind Placebo-Controlled Efficacy Trial

CONTEXT: Cocaine dependence, which affects 2.5 million Americans annually, has no FDA approved pharmacotherapy. OBJECTIVE: To evaluate the immunogenicity, safety, and efficacy of a novel cocaine vaccine to treat cocaine dependence. DESIGN: 24 week Phase IIb randomized double-blind placebo-controlled...

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Detalhes bibliográficos
Main Authors: Martell, Bridget A., Orson, Frank M., Poling, James, Mitchell, Ellen, Rossen, Roger D., Gardner, Tracie, Kosten, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878137/
https://ncbi.nlm.nih.gov/pubmed/19805702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2009.128
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