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Features of a Spatially Constrained Cystine Loop in the p10 FAST Protein Ectodomain Define a New Class of Viral Fusion Peptides

The reovirus fusion-associated small transmembrane (FAST) proteins are the smallest known viral membrane fusion proteins. With ectodomains of only ∼20–40 residues, it is unclear how such diminutive fusion proteins can mediate cell-cell fusion and syncytium formation. Contained within the 40-residue...

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Detalhes bibliográficos
Main Authors: Barry, Christopher, Key, Tim, Haddad, Rami, Duncan, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878076/
https://ncbi.nlm.nih.gov/pubmed/20363742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.118232
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