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Restoration of γ-Sarcoglycan Localization and Mechanical Signal Transduction Are Independent in Murine Skeletal Muscle
Limb girdle muscular dystrophy 2C is caused by mutations in the γ-sarcoglycan gene (gsg) that results in loss of this protein, and disruption of the sarcoglycan (SG) complex. Signal transduction after mechanical perturbation is mediated, in part, through the SG complex and leads to phosphorylation o...
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| Format: | Artigo |
| Language: | Inglês |
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American Society for Biochemistry and Molecular Biology
2010
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878052/ https://ncbi.nlm.nih.gov/pubmed/20371873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063990 |
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