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γ-Sarcoglycan Deficiency Leads to Muscle Membrane Defects and Apoptosis Independent of Dystrophin

γ-Sarcoglycan is a transmembrane, dystrophin-associated protein expressed in skeletal and cardiac muscle. The murine γ-sarcoglycan gene was disrupted using homologous recombination. Mice lacking γ-sarcoglycan showed pronounced dystrophic muscle changes in early life. By 20 wk of age, these mice deve...

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Detalhes bibliográficos
Main Authors: Hack, Andrew A., Ly, Chantal T., Jiang, Fang, Clendenin, Cynthia J., Sigrist, Kirsten S., Wollmann, Robert L., McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149352/
https://ncbi.nlm.nih.gov/pubmed/9732288
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