Hypoxic Tumor Cell Modulates Its Microenvironment to Enhance Angiogenic and Metastatic Potential by Secretion of Proteins and Exosomes

Under hypoxia, tumor cells produce a secretion that modulates their microenvironment to facilitate tumor angiogenesis and metastasis. Here, we observed that hypoxic or reoxygenated A431 carcinoma cells exhibited enhanced angiogenic and metastatic potential such as reduced cell-cell and cell-extracel...

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Detaylı Bibliyografya
Asıl Yazarlar: Park, Jung Eun, Tan, Hon Sen, Datta, Arnab, Lai, Ruenn Chai, Zhang, Huoming, Meng, Wei, Lim, Sai Kiang, Sze, Siu Kwan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2010
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877972/
https://ncbi.nlm.nih.gov/pubmed/20124223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900381-MCP200
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