p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice

Epithelial-cadherin (E-cadherin) is a master organizer of the epithelial phenotype. Its function is regulated in part by p120-catenin (referred to herein as p120), a cytoplasmic binding partner that directly regulates cadherin stability. As it has been suggested that cadherins have a role in inflamm...

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Main Authors: Smalley-Freed, Whitney G., Efimov, Andrey, Burnett, Patrick E., Short, Sarah P., Davis, Michael A., Gumucio, Deborah L., Washington, M. Kay, Coffey, Robert J., Reynolds, Albert B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877948/
https://ncbi.nlm.nih.gov/pubmed/20484816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41414
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