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The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b
Activated protein C (APC), the only FDA-approved biotherapeutic drug for sepsis, possesses anticoagulant, antiinflammatory, and barrier-protective activities. However, the mechanisms underlying its antiinflammatory functions are not well defined. Here, we report that the antiinflammatory activity o...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877939/ https://ncbi.nlm.nih.gov/pubmed/20458145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40380 |
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