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Loss of Transgene following ex vivo Gene Transfer is Associated with a Dominant Th2 Response: Implications for Cutaneous Gene Therapy

Host responses to therapeutic gene products are potentially serious complications in cutaneous gene therapy. Controlling immune responses to the thera-peutic antigen may therefore be critical for an effective therapy. Both ex vivo and in vivo gene transfer to epidermal stem cells has been shown to i...

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Bibliografiske detaljer
Main Authors: Lu, Zhenmei, Ghazizadeh, Soosan
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877884/
https://ncbi.nlm.nih.gov/pubmed/17356544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300086
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