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Loss of Transgene following ex vivo Gene Transfer is Associated with a Dominant Th2 Response: Implications for Cutaneous Gene Therapy
Host responses to therapeutic gene products are potentially serious complications in cutaneous gene therapy. Controlling immune responses to the thera-peutic antigen may therefore be critical for an effective therapy. Both ex vivo and in vivo gene transfer to epidermal stem cells has been shown to i...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877884/ https://ncbi.nlm.nih.gov/pubmed/17356544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300086 |
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