The Insulin-Like Growth Factor Receptor I Promotes Motility and Invasion of Bladder Cancer Cells through Akt- and Mitogen-Activated Protein Kinase-Dependent Activation of Paxillin

The insulin-like growth factor receptor I (IGF-IR) plays an essential role in transformation by promoting cell growth and protecting cancer cells from apoptosis. Aberrant IGF-IR signaling is implicated in several types of tumors, including carcinomas of the lung, breast, prostate, pancreas, liver, a...

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Main Authors: Metalli, David, Lovat, Francesca, Tripodi, Farida, Genua, Marco, Xu, Shi-Qiong, Spinelli, Michela, Alberghina, Lilia, Vanoni, Marco, Baffa, Raffaele, Gomella, Leonard G., Iozzo, Renato V., Morrione, Andrea
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877859/
https://ncbi.nlm.nih.gov/pubmed/20395438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090904
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