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Stimulation of TRPC5 cationic channels by low micromolar concentrations of lead ions (Pb(2+))

Lead toxicity is long-recognised but continues to be a major public health problem. Its effects are wide-ranging and include induction of hyper-anxiety states. In general it is thought to act by interfering with Ca(2+) signalling but specific targets are not clearly identified. Transient receptor po...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sukumar, Piruthivi, Beech, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877782/
https://ncbi.nlm.nih.gov/pubmed/20100462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.01.074
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