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Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease
Increases in heme oxygenase-1 (HO-1) and administration of heme degradation products CO and biliverdin inhibit vascular inflammation and vasoocclusion in mouse models of sickle cell disease (SCD). In this study, an albumin (alb) promoter-driven Sleeping Beauty (SB) transposase plasmid with a wild-ty...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2010
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877767/ https://ncbi.nlm.nih.gov/pubmed/20306336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-010-0613-6 |
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