BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences

BACKGROUND: Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA molecules are usually analyzed, to determine the methylation status at single CpG sites and molecule resolution. RESULTS:...

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Bibliografiske detaljer
Main Authors: Rohde, Christian, Zhang, Yingying, Reinhardt, Richard, Jeltsch, Albert
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
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Software
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877691/
https://ncbi.nlm.nih.gov/pubmed/20459626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-230
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