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Conversion of Adult Pancreatic α-cells to β-cells After Extreme β-cell Loss
Pancreatic insulin-producing β-cells have a long lifespan, such that in healthy conditions they replicate little during a lifetime. Nevertheless, they show increased self-duplication upon increased metabolic demand or after injury (i.e. β-cell loss). It is unknown if adult mammals can differentiate...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877635/ https://ncbi.nlm.nih.gov/pubmed/20364121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08894 |
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