Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types

To identify evolutionarily conserved features of replication timing and their relationship to epigenetic properties, we profiled replication timing genome-wide in four human embryonic stem cell (hESC) lines, hESC-derived neural precursor cells (NPCs), lymphoblastoid cells, and two human induced plur...

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Detalhes bibliográficos
Main Authors: Ryba, Tyrone, Hiratani, Ichiro, Lu, Junjie, Itoh, Mari, Kulik, Michael, Zhang, Jinfeng, Schulz, Thomas C., Robins, Allan J., Dalton, Stephen, Gilbert, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877573/
https://ncbi.nlm.nih.gov/pubmed/20430782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.099655.109
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