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INTERFERON BETA INHIBITS DENDRITIC CELL MIGRATION THROUGH STAT-1 MEDIATED TRANSCRIPTIONAL SUPPRESSION OF CCR7 AND METALLOPROTEINASE 9
Interferon β (IFNβ) is an approved therapeutic option for the treatment of multiple sclerosis (MS). The molecular mechanisms underlying the effects of IFNβ in MS are not fully understood. Migration of dendritic cells (DC) from the inflammatory site to draining lymph nodes for antigen presentation an...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877494/ https://ncbi.nlm.nih.gov/pubmed/20190134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902542 |
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