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PGE2-induced metalloproteinase-9 is essential for dendritic cell migration

Following antigen acquisition and maturation, dendritic cells (DCs) disengage from the extracellular matrix, cross basement membranes, and travel to draining lymph nodes to activate T cells. CCR7 expression is necessary but not sufficient for the directional migration of DCs. Prostaglandin E2 (PGE2)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yen, Jui-Hung, Khayrullina, Tanzilya, Ganea, Doina
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200811/
https://ncbi.nlm.nih.gov/pubmed/17925490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-090613
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