Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation

Nucleophosmin (NPM), an oligomeric phosphoprotein and nucleolar target of the ARF tumor suppressor, contributes to several critical cellular processes. Previous studies have shown that the human NPM’s phosphorylation by cyclin E–cyclin-dependent kinase 2 (cdk2) on threonine (Thr) 199 regulates its t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brady, SN, Maggi, LB, Winkeler, CL, Toso, EA, Gwinn, AS, Pelletier, CL, Weber, JD
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877400/
https://ncbi.nlm.nih.gov/pubmed/19561638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.178
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