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Epidermal Growth Factor Receptor vIII Expression in U87 Glioblastoma Cells Alters Their Proteasome Composition, Function, and Response to Irradiation

Little is known about the factors that influence the proteasome structures in cells and their activity, although this could be highly relevant to cancer therapy. We have previously shown that, within minutes, irradiation inhibits substrate degradation by the 26S proteasome in most cell types. Here,...

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Detalhes bibliográficos
Main Authors: Kim, Kwanghee, Brush, James M., Watson, Philip A., Cacalano, Nicholas A., Iwamoto, Keisuke S., McBride, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877368/
https://ncbi.nlm.nih.gov/pubmed/18337449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-0313
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