Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene

Beta-carotene 15,15′-monooxygenase 1 knockout (Bcmo1 (−/−)) mice accumulate beta-carotene (BC) similarly to humans, whereas wild-type (Bcmo1 (+/+)) mice efficiently cleave BC. Bcmo1 (−/−) mice are therefore suitable to investigate BC-induced alterations in gene expression in lung, assessed by microa...

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Detalhes bibliográficos
Main Authors: van Helden, Yvonne G. J., Heil, Sandra G., van Schooten, Frederik J., Kramer, Evelien, Hessel, Susanne, Amengual, Jaume, Ribot, Joan, Teerds, Katja, Wyss, Adrian, Lietz, Georg, Bonet, M. Luisa, von Lintig, Johannes, Godschalk, Roger W. L., Keijer, Jaap
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877315/
https://ncbi.nlm.nih.gov/pubmed/20372966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0341-7
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