Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene

Beta-carotene 15,15′-monooxygenase 1 knockout (Bcmo1 (−/−)) mice accumulate beta-carotene (BC) similarly to humans, whereas wild-type (Bcmo1 (+/+)) mice efficiently cleave BC. Bcmo1 (−/−) mice are therefore suitable to investigate BC-induced alterations in gene expression in lung, assessed by microa...

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Bibliografski detalji
Glavni autori: van Helden, Yvonne G. J., Heil, Sandra G., van Schooten, Frederik J., Kramer, Evelien, Hessel, Susanne, Amengual, Jaume, Ribot, Joan, Teerds, Katja, Wyss, Adrian, Lietz, Georg, Bonet, M. Luisa, von Lintig, Johannes, Godschalk, Roger W. L., Keijer, Jaap
Format: Artigo
Jezik:Inglês
Izdano: SP Birkhäuser Verlag Basel 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877315/
https://ncbi.nlm.nih.gov/pubmed/20372966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0341-7
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