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Azide–Tetrazole Equilibrium of C-6 Azidopurine Nucleosides and Their Ligation Reactions with Alkynes

[Image: see text] Facile syntheses of C-6 azidopurine ribonucleosides and 2′-deoxyribonucleosides have been developed. For silyl and acetyl protected as well as unprotected nucleosides, access to the azido derivatives could be readily attained via displacement of BtO(−) from the O(6)-(benzotriazol-1...

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Main Authors: Lakshman, Mahesh K., Singh, Manish K., Parrish, Damon, Balachandran, Raghavan, Day, Billy W.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877261/
https://ncbi.nlm.nih.gov/pubmed/20297785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo902342z
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