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Novel β-lactamase-random peptide fusion libraries for phage display selection of cancer cell-targeting agents suitable for enzyme prodrug therapy

Novel phage-displayed random linear dodecapeptide (X(12)) and cysteine-constrained decapeptide (CX(10)C) libraries constructed in fusion to the amino-terminus of P99 β-lactamase molecules were used for identifying β-lactamase-linked cancer cell-specific ligands. The size and quality of both librarie...

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Bibliografiske detaljer
Main Authors: Shukla, Girja S., Krag, David N.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877152/
https://ncbi.nlm.nih.gov/pubmed/19751096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10611860903244181
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